Spotlight: Lessons and legacy from Europe's most ambitious decentralised CAR-T model

What it takes to build a decentralised CAR-T manufacturing model in practice, and where the original “point-of-care” vision met operational reality.

Key lessons from running multi-site GMP manufacturing, including comparability, consistency, and control across a distributed network.

How regulatory expectations, potency requirements, and analytical strategy evolved—and shaped what was possible in a decentralised setup.

Why the programme ultimately wound down, what alternatives were explored, and which elements of the model still have value for the wider CGT field.