Spotlight: Why scaling CGT production is no longer the hard part and what now determines commercial success

Capacity solved, complexity exposed: Why increasing CGT manufacturing capacity alone doesn’t unlock commercial success and how variability, flexibility and operational friction now limit real-world adoption.

Cost is shaped upstream, not at launch: How manufacturing design choices (automation, standardisation, tech transfer models) determine long-term cost of goods and why many programmes lock in commercial constraints far too early.

Industrialising without over-engineering: Where teams overbuild manufacturing systems that don’t match demand, and how smarter, modular and adaptable approaches support both early launches and long-term portfolio growth.

Manufacturing as a commercial lever: How robust, repeatable production directly influences payer confidence, hospital readiness and willingness to adopt and why manufacturing strategy must now align with access strategy.

What ‘commercial-ready manufacturing’ really means: The capabilities CGT programmes need before approval comparability, change control, scalability and supply reliability to avoid post-launch resets.