Moving from discovery to clinic with next generation translational strategies

Translating innovative research into early clinical programs requires structured strategies that connect discovery outputs with clinical objectives. This spotlight presentation highlights methods to integrate translational insights, optimize biomarker strategies, and improve decision-making across program stages.

Key takeaways

• Apply next-generation frameworks to strengthen translational fidelity from discovery to clinic
• Define dose selection and biomarker strategies that inform early clinical studies
• Integrate PK and PD data to enhance predictive validity for human subjects
• Establish workflows that support rapid iteration without compromising safety
• Align discovery outputs with program readiness and regulatory expectations