Navigating the Road Ahead for In Vivo CAR-T: An Interactive Roundtable

“In vivo CAR-T has the potential to transform cell therapy by enabling faster, more accessible treatments, however with this new therapeutic opportunities we must anticipate technical, clinical, and regulatory considerations that define its path forward This interactive roundtable will explore how to successfully navigate this innovative modality by participating in three breakout discussions:

De-risking development pathways:

Let’s discuss and navigate key decisions in in vivo CAR-T development—delivery platforms (LVV vs. LNP), bottlenecks, and strategic partnerships—to accelerate progress while minimizing risk.

Patient safety & Experience:

What does “safety” mean for in vivo CAR-T and how do we get there? Share and explore perspectives on dosing, monitoring, consent, and ethics.

Defining In Vivo CAR-T Success:

Let’s envision the future of in vivo CAR-T. Let’s dive into the real-world impact, and brainstorm innovations, regulatory pathways, and ecosystems needed for scalable success. “