Spotlight session: Exploring novel cell sources to overcome limitations in current modalities

Developers are increasingly looking beyond traditional cell types to unlock new opportunities for advanced therapies. Novel cell sources could enable improved manufacturing consistency, broaden patient eligibility, and enhance translational fidelity. This spotlight session examines scientific and strategic considerations for integrating alternative cell sources into development pipelines. 

Key takeaways: 

• Assess the limitations of current cell therapy modalities and where novel sources can provide solutions. 

• Explore how alternative cell sources impact scalability and manufacturing reproducibility. 

• Examine translational fidelity and predictive validity considerations for new platforms. 

• Discuss safety margins and biomarker strategies for non-traditional cell therapies. 

• Consider regulatory perspectives on adopting novel cell sources in advanced therapy development.