Spotlight session: Translational insights from early trials in diverse patient populations

Understanding how therapies perform across diverse patient populations is critical to ensuring translational validity and improving trial outcomes. This session will share insights from early clinical studies, focusing on how demographic and biological diversity shapes safety, efficacy, and trial strategy. 

Key Takeaways:  

• Assess the impact of patient diversity on translational fidelity and predictive validity 

• Examine how demographic variability influences dose selection and biomarker strategy 

• Understand challenges of recruiting and retaining diverse patient populations in early trials 

• Apply lessons from early studies to improve trial design and regulatory readiness 

• Strengthen clinical development strategies by integrating diverse patient data